High-fat foods will increase CBD absorption into the body

High-fat foods will increase CBD absorption into the body

While CBD capsules were approved by the U.S. Food and Drug Administration (FDA) for use in patients with seizures in 2018, very little was known about the effect of food on CBD absorption.

A University of Minnesota study, published in Epilepsia, examined whether eating high-fat foods after taking CBD increased the body's absorption of CBD. The study tested whether fasting or a high-fat meal has an effect when cannabidiol oral capsules were taken by patients.

To find out what impact a fatty meal would wear CBD absorption, the analysis cluster measured CBD concentrations in brain disease patients at the MINCEP brain disease Care clinic UN agency were taking 99 percent pure CBD capsules. Concentrations from patients UN agency took CBD on AN empty abdomen and the same fatty breakfast (i.e. breakfast burrito) were compared.

"The form of food will create an oversized distinction within the quantity of CBD that gets absorbed into the body. Although fatty foods can increase the absorption of CBD, it can also increase the variability as not all meals contain the same amount of fat," said Angela Birnbaum, a professor in the College of Pharmacy and study co-author.

"Increases within the quantity of the CBD dose being absorbed into the body may also result in lower medication prices," aforesaid UN agency Leppik, study author, an academic within the school of Pharmacy and an adjunct professor at the Medical School.


The study found:

  • CBD exposure is vastly increased when CBD is taken with high fatty foods;
  • when compared to fast, taking CBD with food increased the amount of CBD in the body by four-times and the maximum amount recorded in the participants' blood by 14-times;
  • no cognitive differences were identified, which is consistent with previous studies.

"For epilepsy patients, a goal is to maintain consistent blood concentrations of the drug," said Birnbaum. "This study shows that CBD concentrations may vary considerably if patients take it otherwise, sometimes with or without food. Variations in blood concentrations may leave a patient a lot of at risk of seizures."